Studie: geen verband tussen autisme en XMRV?
Geplaatst: 17 nov 2010, 22:07
PCR and serology find no association between xenotropic murine leukemia virus-related virus (XMRV) and autismBrent C Satterfield1 , Rebecca A Garcia1 , Fiorella Gurrieri2 and Charles E Schwartz3
1 Cooperative Diagnostics, LLC, Greenwood, SC 29646, USA
2 Institute of Medical Genetics, Catholic University, Rome, Italy
3 Greenwood Genetic Center, Greenwood, SC 29646, USA
author email corresponding author email
Molecular Autism 2010, 1:14doi:10.1186/2040-2392-1-14
The electronic version of this article is the complete one and can be found online at: http://www.molecularautism.com/content/1/1/14
Received: 14 May 2010
Accepted: 14 October 2010
Published: 14 October 2010
Lees de studie hier
Autistische kinderen geboren uit moeders met ME/CVS testen allemaal negatief op XMRV
However, after analyzing the samples from 25 autistic children born to mothers with CFS and 20 mixed controls, there was no evidence of XMRV infection in any of the PCR assays
(Table 2). No anti-XMRV antibodies were detected in these samples either, ruling out low-level infections that might have been missed by PCR. Additional assaying of AD, ASD and healthy control samples by real-time PCR revealed no evidence of XMRV infection. In all, 230 autism samples and 204 controls gave negative PCR results for XMRV.
Ter info:
Cooperative Diagnostics is a commercial enterprise that owns the rights to the XMRV real-time PCR assay described in this manuscript, in addition to the Master Mix that was used. Publication of these results may well reduce the potential market that Cooperative Diagnostics could reach with its XMRV assay.
1 Cooperative Diagnostics, LLC, Greenwood, SC 29646, USA
2 Institute of Medical Genetics, Catholic University, Rome, Italy
3 Greenwood Genetic Center, Greenwood, SC 29646, USA
author email corresponding author email
Molecular Autism 2010, 1:14doi:10.1186/2040-2392-1-14
The electronic version of this article is the complete one and can be found online at: http://www.molecularautism.com/content/1/1/14
Received: 14 May 2010
Accepted: 14 October 2010
Published: 14 October 2010
Lees de studie hier
Autistische kinderen geboren uit moeders met ME/CVS testen allemaal negatief op XMRV
However, after analyzing the samples from 25 autistic children born to mothers with CFS and 20 mixed controls, there was no evidence of XMRV infection in any of the PCR assays
(Table 2). No anti-XMRV antibodies were detected in these samples either, ruling out low-level infections that might have been missed by PCR. Additional assaying of AD, ASD and healthy control samples by real-time PCR revealed no evidence of XMRV infection. In all, 230 autism samples and 204 controls gave negative PCR results for XMRV.
Ter info:
Cooperative Diagnostics is a commercial enterprise that owns the rights to the XMRV real-time PCR assay described in this manuscript, in addition to the Master Mix that was used. Publication of these results may well reduce the potential market that Cooperative Diagnostics could reach with its XMRV assay.
