Nou het mag dan DE theorie van Pall heten, maar dat wil niet zeggen, dat het niet wetenschappelijk onderzocht is. De man heeft n.a.v. dat feit boeken vol geschreven.
Zie zijn laatste boek op bijvoorbeeld:
http://www.hetalternatief.org/Theorie%20Pall.htm
Over de hele wereld is er dergelijk onderzoek gedaan, niet alleen door Pall. Dirk noemde al een paar, maar er zijn er veel meer.
Dit is van Spence bijvoorbeeld:
Oxidative stress levels are raised in chronic fatigue syndrome
and are associated with clinical symptoms
Free Radical Biology & Medicine 2005; 39(5): 584-9
G Kennedy, VA Spence, M McLaren, A Hill, C Underwood, JJF Belch
Introduction:
The aetiology of chronic fatigue syndrome (CFS) is unknown; however, recent evidence suggests that excessive free radical (FR) generation may be involved. This study investigated for the first time levels of 8-iso-prostaglandin-F2a-isoprostanes alongside other plasma markers of oxidative stress in CFS patients and control subjects.
Methods:
Forty-seven patients (18 males, 29 females, mean age 48 [19–63] years) who fulfilled the Centres for Disease Control classification for CFS and 34 healthy volunteers (13 males, 21 females, 46 [19–63] years) were enrolled in the study. The CFS patients were divided into two groups; one group had previously defined cardiovascular (CV) risk factors of obesity and hypertension (group 1) and the second were normotensive and nonobese (group 2).
Results:
Patients had significantly increased levels of isoprostanes (group 1, P = 0.007; group 2, P = 0.03, unpaired t test compared to controls) and oxidised low-density lipoproteins (group 2, P = 0.02) indicative of a FR attack on lipids. CFS patients also had significantly lower high-density lipoproteins (group 1, P = 0.011; group 2, P = 0.005). CFS symptoms correlated with isoprostane levels, but only in group 2 low CV risk CFS patients (isoprostanes correlated with; total symptom score P = 0.005; joint pain P = 0.002; postexertional malaise P = 0.027, Pearson).
Conclusion:
This is the first time that raised levels of the gold standard measure of in vivo oxidative stress (isoprostanes) and their association with CFS symptoms have been reported.
Van wikipedia:
http://en.wikipedia.org/wiki/Chronic_fa ... ive_stress
[edit] Oxidative stress
Further information: Oxidative stress
Oxidative stress is an imbalance between the production of reactive oxygen and a biological system's ability to readily detoxify the reactive intermediates or easily repair the resulting damage.
Several studies[83][84][85][86][87][88] and a review[89] have implicated oxidative stress in CFS symptoms; especially relating to fatigue, pain and postexertional malaise / exercise intolerance. According to researchers of one study, the findings on oxidative stress (and nitric oxide-related toxicity) seem consistent with their findings of the abnormal 2-5A synthetase/RNase L enzyme (antiviral) activity which has previously been implicated in the pathology of exercise intolerance in CFS.[90]
of deze:
http://www.immunesupport.com/library/sh ... fm/ID/8399
Antiviral Pathway Deregulation of Chronic Fatigue Syndrome Induces Nitric Oxide Production in Immune Cells That Precludes a Resolution of the Inflammatory Response
These results therefore suggest that chronic inflammation due to excess nitric oxide production plays a role in CFS and that the normal resolution of the inflammatory process by NF-kB activation and apoptotic induction is impaired. These observations draw new directions for the therapeutic approach of CFS.
En dit is dan maar een handje vol zeg maar, maar anders wordt het zo vol hier he. Bovendien alles Engels en betrekkelijk ingewikkeld.
Die studies van Wikipedia staan overigens natuurlijk op die site.
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