In een redactionele bijdrage van Bridget M. Kuehn in het toptijdschrift JAMA wordt melding gemaakt van de volgende hoopgevende (?) feiten.
1. De studie van Lo en Alter wordt serieus genomen:
"Lo and colleagues went to great lengths to ensure that the results were not caused by contamination. For example, the blood samples used came from laboratories that had never worked with mice or retroviral vectors, and testing of the samples was conducted in
laboratories that had never worked with mouse cells, tissues, or serum samples, or vectors of the murine leukemia virus. The samples that tested positive for murine leukemia–related viruses were tested to determine whether they were contaminated with mouse DNA. Additionally, the authors noted that if contamination had occurred, the various
samples would likely show the same gene sequence; however, they found at least 6 different murine leukemia virus–related gene sequences that appear distinct from those previously reported. They also used virus-negative controls"
2. Alter is er nog niet mee opgehouden! Leidt dat wederom tot bevestiging door een autoriteit???
"Alter said his group has a study in progress looking for the virus and antibodies to it in samples from 1000 donors. They also have frozen samples taken from blood recipients before and after transfusion and have linked them to donors. “We will be looking at those
samples to see if we can demonstrate any transmission,” he said".
In het schrijven wordt helaas ook verschillende malen gerefereerd aan Schaffner een scepticus.... die voor het gemak de patienten maar weer eens de schuld geeft van het falen van de NIH en de CDC.
"Schaffner said it would be helpful for the NIH to recruit additional well qualified researchers to the CFS field.
He explained that many investigators may have shied away from the area in the past because they were uncertain about the disease or were concerned about dealing with passionate members of support organizations devoted to the illness."
Bron:
With Chronic Fatigue Syndrome
Study Reignites Debate About Viral Agent in Patients
JAMA. 2010;304(15):1653-1656 (doi:10.1001/jama.2010.1421)
Redactionele bijdrage JAMA: hoopgevend?
Moderator: Moderators